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Mylotarg, gemtuzumab ozogamicin

Also known as: CMA-676

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Company Pfizer Inc.
DescriptionCombination of calicheamicin with a humanized mAb that targets CD33-expressing cancer cells
Molecular Target CD33
Mechanism of ActionAntibody-drug conjugate
Therapeutic ModalityBiologic: Antibody-drug conjugate
Latest Stage of DevelopmentMarketed
Standard IndicationAcute myelogenous leukemia (AML)
Indication DetailsTreat acute myelogenous leukemia (AML); Treat CD33-positive relapsed acute myelogenous leukemia (AML); Treat refractory acute myelogenous leukemia (AML)
Regulatory Designation
PartnerUCB Group

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