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CK-101, RX518

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Company Suzhou NeuPharma Co. Ltd.
DescriptionThird-generation covalent inhibitor of EGFR-activating mutations and the T790M EGFR resistance mutation
Molecular Target Epidermal growth factor receptor (EGFR)
Mechanism of ActionEpidermal growth factor (EGF) receptor inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPreclinical
Standard IndicationNon-small cell lung cancer (NSCLC)
Indication DetailsTreat non-small cell lung cancer (NSCLC)
Regulatory Designation
PartnerCheckpoint Therapeutics Inc.;
Fortress Biotech Inc.

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