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IV solithromycin (CEM-101) (formerly OPT-1068)

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Company Merck & Co. Inc.
DescriptionIV formulation of a fluoroketolide/macrolide antibiotic
Molecular Target Ribosomal 50S subunit
Mechanism of ActionRibosomal 50S subunit inhibitor
Therapeutic ModalityMacrocycle
Latest Stage of DevelopmentPhase III
Standard IndicationPneumonia
Indication DetailsTreat community-acquired bacterial pneumonia (CABP); Treat moderate to severe community-acquired bacterial pneumonia (CABP)
Regulatory Designation U.S. - Fast Track (Treat community-acquired bacterial pneumonia (CABP))
Partner Cempra Inc.; Toyama Chemical Co. Ltd.

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