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Opgenra (BMP-7, OP-1)

Also known as: Osteogenic protein-1 (OP-1)

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Company Olympus Biotech Corp.
DescriptionBone morphogenic protein 7 (BMP7)
Molecular Target Bone morphogenetic protein 7 (BMP7) (OP-1) ; Bone morphogenetic protein receptor type II (BMPRII)
Mechanism of ActionBone morphogenic protein (BMP) type II receptor agonist
Therapeutic ModalityBiologic: Protein
Latest Stage of DevelopmentMarketed
Standard IndicationBone repair
Indication DetailsBone defect repair in osteoarthritis (OA); Bone graft; Joint regeneration; Treat posterolateral lumbar spinal Fusion (PLF) in adult patients with spondylolisthesis where autograft has failed or is contraindicated.; Treat bone disease and vascular calcification associated with chronic kidney disease (CKD); Treat long bone non-unions; Treat long bone unions; Treat non-union bone fractures; Treat non-union fractures; Treat non-union tibial fractures; Treat vascular calcification in chronic kidney disease (CKD) patients
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