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BLU-285

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Company Blueprint Medicines Corp.
DescriptionInhibitor of stem cell factor (SCF) receptor tyrosine kinase (c-Kit; KIT; CD117) exon 17 mutations and platelet derived growth factor receptor A (PDGFRA; PDGFR2; CD140A) with the D842V amino acid substitution
Molecular Target Stem cell factor (SCF) receptor tyrosine kinase (c-Kit) (KIT) (CD117) ; Platelet derived growth factor receptor A (PDGFRA) (PDGFR2) (CD140A)
Mechanism of ActionStem cell factor (SCF) receptor tyrosine kinase (c-Kit) (KIT) (CD117) inhibitor; Platelet derived growth factor receptor A (PDGFRA) inhibitor
Therapeutic ModalitySmall molecule

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