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Vargatef, nintedanib (Ofev) (BIBF 1120)

Also known as: BIBF1120

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Company Boehringer Ingelheim GmbH
DescriptionSmall molecule inhibitor of multiple pro-angiogenic kinases, including VEGF, platelet derived growth factor receptor (PDGFR) and fibroblast growth factor (FGF) receptor (FGFR)
Molecular Target Vascular endothelial growth factor (VEGF) receptor ; Platelet derived growth factor receptor (PDGFR)
Mechanism of ActionPlatelet derived growth factor receptor (PDGFR) kinase inhibitor; Vascular endothelial growth factor (VEGF) receptor inhibitor
Therapeutic ModalitySmall molecule

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