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bevenopran (formerly ADL5945, CB-5945, OpRA III)

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Collapse Summary General Information
Company Eli Lilly and Co.
DescriptionMu opioid receptor (OPRM1; MOR) antagonist
Molecular Target Mu opioid receptor (OPRM1) (MOR)
Mechanism of ActionMu opioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase III
Standard IndicationConstipation
Indication DetailsTreat opioid-induced constipation (OIC)
Regulatory Designation

Partner

Cubist Pharmaceuticals Inc.


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