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Beriplex (4-factor prothrombin complex concentrate (PCC), Kcentra)

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Company CSL Ltd.
DescriptionProthrombin complex concentrate containing Factors II, VII, IX and X, as well as anticoagulant Proteins C and S
Molecular Target
Mechanism of ActionReverse anticoagulant
Therapeutic ModalityBiologic
Latest Stage of DevelopmentMarketed
Standard IndicationBleeding
Indication DetailsReversal of anticoagulation with vitamin K antagonist therapy, including warfarin, in adults needing an urgent surgery or other invasive procedure; Reversal of vitamin K antagonist therapy in patients with acute major bleeding; Reversal of warfarin therapy
Regulatory Designation


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