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Axelopran/oxycodone FDC

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Company Theravance Biopharma Inc.
DescriptionFixed-dose combination (FDC) of axelopran (TD-1211), an oral peripheral mu opioid receptor (MOR; OPRM1) antagonist, and controlled-release oxycodone
Molecular Target Mu opioid receptor (MOR) (OPRM1)
Mechanism of Action 
Therapeutic Modality 
Latest Stage of DevelopmentPhase I
Standard IndicationPain
Indication DetailsTreat pain and opioid-induced constipation (OIC)
Regulatory Designation

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