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Company Otsuka Pharmaceutical Co. Ltd.
DescriptionSmall molecule inhibitor of aurora kinase A and B, Janus kinase-2 (JAK-2), FMS-like tyrosine kinase 3 (FLT3) and Abl T315I
Molecular Target Aurora kinase A (AURKA) (Aurora-A) ; Aurora kinase B (AURKB) (Aurora-B)
Mechanism of ActionFMS-like tyrosine kinase 3 (FLT3) inhibitor; Aurora kinase inhibitor; Janus kinase-2 (JAK-2) inhibitor
Therapeutic ModalitySmall molecule

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