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leflunomide (Arava)

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Company Sanofi
DescriptionInhibitor of pyrimidine synthesis
Molecular Target Dihydroorotate dehydrogenase (DHODH)
Mechanism of ActionDihydroorotate dehydrogenase (DHODH) inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationRheumatoid arthritis (RA)
Indication DetailsImprove physical function in patients with rheumatoid arthritis (RA); Treat active rheumatoid arthritis (RA); Treat rheumatoid arthritis (RA)
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