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Amyvid, florbetapir (18F-AV-45) (formerly Florpiramine)

Also known as: AV-45, F-AV-45

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Collapse Summary General Information
Company Eli Lilly and Co.
DescriptionImaging agent labeled with fluorine 18 (F-18) that binds to amyloid plaques
Molecular Target Beta amyloid
Mechanism of ActionDiagnostic; Imaging agent
Therapeutic ModalityDiagnostics
Latest Stage of DevelopmentMarketed
Standard IndicationNeurology, Diagnostic
Indication DetailsDiagnose Alzheimer's disease (AD); Estimate beta amyloid neuritic plaque density in patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) and other causes of cognitive decline
Regulatory Designation

U.S. - Priority Review (Estimate beta amyloid neuritic plaque density in patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) and other causes of cognitive decline)

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