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Latiglutenase (IMGX-003) (formerly ALV-003, ALV003)

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Company Immunogenics LLC
DescriptionCombination of a cysteine protease (EP-B2) and a proline-specific prolyl endopeptidase (PEP) engineered to degrade gluten into non-immunotoxic fragments
Molecular Target Gluten
Mechanism of ActionDegrades protein
Therapeutic ModalityBiologic: Enzyme
Latest Stage of DevelopmentPhase II
Standard IndicationCeliac disease
Indication DetailsTreat celiac disease
Regulatory Designation U.S. - Fast Track (Treat celiac disease)
PartnerAbbVie Inc.

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