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Altropane (NAV5001)

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Company Alseres Pharmaceuticals Inc.
DescriptionIodine-123-labeled radiopharmaceutical used with SPECT imaging that binds to dopamine transporter sites in the brain
Molecular Target Dopamine transporter
Mechanism of ActionDiagnostic; Imaging agent
Therapeutic ModalityDiagnostics
Latest Stage of DevelopmentPhase III
Standard IndicationNeurology, Diagnostic
Indication DetailsAid in the differential diagnosis of Parkinsonian syndromes from non-Parkinsonian tremor; Diagnose dementia with Lewy bodies (DLB); Diagnose early-stage Parkinson's disease (PD); Diagnose Parkinson's disease (PD) using single photon emission computed tomography (SPECT) or positron emission tomography (PET); Differentiate Parkinsonian syndrome tremors from non-Parkinsonian tremors; Imaging agent to assess loss of dopamine receptors in Parkinson's disease (PD)
Regulatory Designation

U.S. - Special Protocol Assessment (Aid in the differential diagnosis of Parkinsonian syndromes from non-Parkinsonian tremor)

Partner

Navidea Biopharmaceuticals Inc.; Sterigenics International Inc.


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