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ALS-2200, VX-135

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Company Johnson & Johnson
DescriptionNucleotide HCV NS5B polymerase inhibitor
Molecular Target HCV NS5B polymerase
Mechanism of ActionHCV non-structural protein 5B inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationHepatitis C virus (HCV)
Indication DetailsTreat chronic HCV infection; Treat HCV genotype 1 infection; Treat HCV infection; Treat non-cirrhotic, treatment-naïve patients with chronic HCV genotype 1 infection
Regulatory Designation


Vertex Pharmaceuticals Inc.

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