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rucaparib (CO-338) (formerly AG-014699, PF-01367338)

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Company Pfizer Inc.
DescriptionOral inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2
Molecular Target Poly(ADP-ribose) polymerase-1 (PARP-1) ; Poly(ADP-ribose) polymerase-2 (PARP-2)
Mechanism of ActionPoly(ADP-ribose) polymerase-1 (PARP-1) inhibitor
Therapeutic ModalitySmall molecule

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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