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Qapzola, apaziquone (EOquin)

Also known as: formerly EO9, Neoquin

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Collapse Summary General Information
Company Spectrum Pharmaceuticals Inc.
DescriptionAnalog of mitomycin C that is reduced by intracellular reductases into active DNA-damaging moieties
Molecular Target DNA
Mechanism of ActionBreaks/crosslinks DNA
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentRegistration
Standard IndicationBladder cancer
Indication DetailsTreat bladder cancer; Treat non-muscle invasive bladder cancer (NMIBC); Treat recurrent superficial bladder cancer (SBC); Treat superficial bladder cancer (SBC)
Regulatory Designation U.S. - Special Protocol Assessment (Treat non-muscle invasive bladder cancer (NMIBC));
U.S. - Standard Review (Treat non-muscle invasive bladder cancer (NMIBC))
PartnerHandok Inc.;
Nippon Kayaku Co. Ltd.

 Product Details
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Collapse Summary Deals Information
Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

2

$151.0M

$15.0M

$136.0M


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone

12/07/2009

Undisclosed

Undisclosed

Undisclosed

11/16/2009

$151.0M

$15.0M

$136.0M

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