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Orvepitant (formerly GW823296)

Also known as: formerly 823296

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Company NeRRe Therapeutics Ltd.
DescriptionNeurokinin 1 (NK1) receptor antagonist
Molecular Target Neurokinin 1 (NK1) substance P receptor (TACR1)
Mechanism of ActionNeurokinin-1 (NK-1) (Substance P) receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationItch
Indication DetailsTreat intense pruritus (itch) associated with epidermal growth factor receptor inhibitor (EGFRi) anticancer therapies
Regulatory Designation

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