BioCentury
ARTICLE | Translation in Brief

Antibiotic among fungi

An antibiotic has efficacy against fungal infections

November 19, 2015 8:00 AM UTC

A Canadian team has developed a network of antifungal-compound interactions, termed the Antifungal Combination Matrix, and identified an antibiotic that has activity against fungal infections.

The team began by performing high throughput combination screens of sublethal doses of six known antifungals with over 3,000 bioactive molecules in cultures of multiple species of fungi. The screen identified 86,000 pairs of molecule interactions and 1,550 compound combinations that showed efficacy against one or more fungal species. ...