Table 1. Stand Up To Cancer awards. The charity will pay out $73.6 million over 3 years to 5 groups of cancer researchers.


Team leaders


Research focus


Grant ($M)


Craig Thompson, Abramson Cancer Center of the University of Pennsylvania;
Daniel Von Hoff, The Translational Genomics Research Institute


Use advanced imaging techniques to determine what nutrients pancreatic cancer cells require for growth and survival and run clinical trials designed to deprive pancreatic tumors of crucial nutrients in combination with standard chemotherapy




Joe Gray, Lawrence Berkeley National Laboratory;
Dennis Slamon, University of California, Los Angeles


Develop therapies for the three major subtypes of breast cancer and design a discovery platform for identifying and validating new molecular targets and breast cancer drug combinations




Lewis Cantley, Beth Israel Deaconess Medical Center;
Charles Sawyers, Memorial Sloan-Kettering Cancer Center;
Gordon Mills, The University of Texas M.D. Anderson Cancer Center


Use biomarkers and imaging techniques to identify breast, ovarian and endometrial cancer patients who could benefit from phosphoinositide 3-kinase (PI3K) inhibitors and develop therapeutic combinations that hit multiple targets in cellular pathways that contribute to tumor growth




Daniel Haber, Massachusetts General Hospital Cancer Center; Mehmet Toner, Harvard Medical School


Optimize chip technology for detecting circulating tumor cells in a large-scale clinical setting and conduct clinical trials to assess the chip's ability to detect early cancers and monitor tumor treatment response




Stephen Baylin, The Sidney Kimmel Comprehensive Cancer Center; Peter Jones, University of Southern California


Identify biomarkers that can predict and monitor the efficacy of epigenetic cancer therapies, develop therapies that target cancer stem cells and design a clinical trial to test the efficacy of a second-generation epigenetic anticancer compound