Thursday, September 19, 2013
Austrian researchers grabbed headlines
last month when they coaxed cultured human induced pluripotent stem cells into
forming brain tissue,1 but in actuality the approach does not offer
applications beyond studying very early brain development.
Knoblich's findings are a step toward
developing in vitro models of neurological disease, but the precise
conditions in which the model should be applicable is up for debate.
Osherovich, L. SciBX 6(36); doi:10.1038/scibx.2013.984
Published online Sept. 19, 2013
1. Lancaster, M. et al.
Nature; published online Aug. 28, 2013; doi:10.1038/nature12517
Contact: Jürgen Knoblich, Institute of Molecular Biotechnology of the
Austrian Academy of Sciences, Vienna, Austria
2. Sato, T. et al.
Nature 459, 262-265 (2009)
3. Dekkers, J.F. et al.
Nat. Med. 19, 939-945 (2013)
4. Takebe, T. et al.
Nature 499, 481-484 (2013)
5. Eiraku, M. et al.
Nature 472, 51-56 (2011)
6. Muguruma, K. et al.
Nat. Neurosci. 13, 1171-1180 (2010)
AND INSTITUTIONS MENTIONED
GlaxoSmithKline plc (LSE:GSK; NYSE:GSK), London, U.K.
Institute of Molecular Biotechnology of the Austrian
Academy of Science,
One Mind for Research, Seattle, Wash.
Massachusetts Institute of Technology, Cambridge, Mass.