ARTICLE | Tools & Techniques
Flick of the switch
September 15, 2011 7:00 AM UTC
Researchers from The Rockefeller University have developed an antibody-engineering technique that increases the antitumor potency of an agonistic anti-CD40 mAb.1 The method involves switching
Fc g-receptor IIb, an antibody co-receptor that binds to the invariant region of antibodies, from an inhibitor to a promoter of immune cell activation...