ARTICLE | Distillery Therapeutics
Therapeutics: Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2); MLL-AF9 fusion oncogene
July 21, 2016 7:00 AM UTC
Cell culture and mouse studies suggest inhibiting MTHFD2 could help treat AML. In human AML cell lines, shRNA targeting MTHFD2 decreased proliferation and colony formation compared with scrambled shRN...