BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Src homology protein tyrosine phosphatase 2 (SHP-2; SHPTP2; PTPN11); receptor tyrosine kinase (RTK)

July 14, 2016 7:00 AM UTC

In vitro, cell culture and mouse studies identified a SHP-2 inhibitor that could help treat cancers and leukemias harboring RTK mutations. Small molecule library screening using an in vitro enzymatic ...