BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: μ opioid receptor (MOR; OPRM1); opioid receptor δ 1 (OPRD1; DOR)

January 21, 2016 8:00 AM UTC

In vitro and mouse studies identified a tetrahydroquinoline-based MOR agonist and DOR antagonist that could help treat pain. Chemical synthesis of tetrahydroquinoline analogs and testing in competitiv...