BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Myeloid-lymphoid or mixed-lineage leukemia (MLL; HRX); p53

October 8, 2015 7:00 AM UTC

In vitro and patient sample studies suggest inhibiting MLL could help treat p53-mutant cancers. In a human breast cancer cell line expressing a p53 mutation, the mutant protein bound and up-regulated ...