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ARTICLE | Distillery Therapeutics

Therapeutics: Toll-like receptor 4 (TLR4)

June 25, 2015 7:00 AM UTC

In vitro and rat studies suggest a TLR4-inhibiting naltrexone analog could help treat pain. Chemical synthesis of naltrexone analogs and testing in a mouse microglia-based assay of TLR4-mediated nitri...