BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Metabotropic glutamate receptor subtype 5 (mGluR5; GRM5);

June 4, 2015 7:00 AM UTC

In vitro and rat studies identified a positive allosteric modulator (PAM) of mGluR5 that could help treat schizophrenia. Optimization of a previously identified mGluR5 PAM and testing in rat astrocyte...