BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Yes-associated protein 1 (YAP1; YAP); SRY (sex determining region Y)-box 2 (SOX2)

April 16, 2015 7:00 AM UTC

In vitro and mouse studies suggest inhibiting YAP could help treat osteosarcoma and other SOX2-expressing cancers. Human and mouse osteosarcoma cell lines, which express high levels of SOX2, had highe...