ARTICLE | Distillery Therapeutics
Therapeutics: Phosphodiesterase-4 (PDE-4); sonic hedgehog (SHH)
April 16, 2015 7:00 AM UTC
In vitro and zebrafish studies suggest PDE-4 inhibitors could help treat cancers that involve overactive hedgehog signaling. A chemical screen in zebra embryos and in vitro testing of the lead hit, eg...