BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Triggering receptor expressed on myeloid cells 2 (TREM2)

April 9, 2015 7:00 AM UTC

In vitro and mouse studies suggest inhibiting TREM2 could help treat AD. In two mouse models of AD, TREM2 was expressed on monocytes of peripheral origin that accumulate around β-amyloid (Aβ) plaques ...