BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A)

March 26, 2015 7:00 AM UTC

In vitro and mouse studies suggest DYRK1A inhibitors could help treat diabetes. In human islets and rat β cells, the DYRK1A inhibitor harmine or shRNA targeting DYRK1A increased proliferation compared...