BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Two pore segment channel 1 (TPCN1); TPCN2

March 19, 2015 7:00 AM UTC

In vitro and mouse studies suggest inhibiting TPCN1 and TPCN2 could help treat Ebola. In HeLa cells, the calcium channel blocker tetrandine disrupted TPCN1- and TCPN2-dependent endosomal trafficking o...