BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Tyrosyl tRNA synthetase (YARS; TyrRS); poly(ADP-ribose) polymerase-1 (PARP-1)

March 12, 2015 7:00 AM UTC

In vitro and mouse studies suggest targeting YARS or PARP-1 could help treat diabetes. The sirtuin1 (SIRT1)-activating agent resveratrol has cell-protecting effects in diabetes and other diseases. In ...