BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Peptidyl arginine deiminase (PADI; PAD); PADI type IV (PADI4, PAD4)

March 12, 2015 7:00 AM UTC

In vitro studies have identified PADI inhibitors that could help treat autoimmune diseases and cancer. A chemical screen identified multiple chloro-amidine analogs that inhibited PADI4 and three other...