BioCentury
ARTICLE | Distillery Techniques

Techniques: Parallel, cell-based shRNA and CRISPR screening to predict on- and off-targets of drug compounds

April 21, 2016 7:00 AM UTC

Parallel shRNA- and CRISPR-based screening in human cells could help identify the on- and off-targets of drug compounds. The method utilized two human cell lines in parallel: one transfected with an s...