BioCentury
ARTICLE | Distillery Techniques

Techniques: ATP binding cassette subfamily A member 7 (ABCA7)-knockout mouse model of Alzheimer's disease (AD)

April 7, 2016 7:00 AM UTC

Mice with knockout of the ABCA7 gene could be useful for screening therapies to treat AD. Loss-of-function mutations in ABCA7 are risk markers for AD. Aged ABCA7-knockout mice showed memory deficits a...