BioCentury
ARTICLE | Distillery Techniques

Techniques: Co-crystal structure of fat mass and obesity associated (FTO) bound to an inhibitor

October 8, 2015 7:00 AM UTC

The co-crystal structure of human FTO bound to an inhibitor could aid the design of FTO inhibitors to treat obesity. A screen of benzenediol derivatives in an FTO inhibition assay identified a compoun...