ARTICLE | Distillery Techniques
Techniques: Presenilin 1 (PSEN1)-knockin mouse model of Alzheimer's disease (AD)
April 2, 2015 7:00 AM UTC
Mice expressing a transgenic mutation of PSEN1 could be used to screen for therapies to treat AD. In mice, heterozygous knock-in of a human PSEN1 mutation associated with familial AD decreased cortica...