Thursday, May 1, 2014
Publication and contact
Asthma diagnostic based on
neutrophil chemotaxis speed
A handheld microfluidic
device that measures neutrophil chemotaxis speed could help diagnose asthma.
The device separates neutrophils from whole blood and stimulates neutrophil
chemotaxis with a chemoattractant. It detected decreased chemotaxis in neutrophils
from mildly asthmatic patients compared with neutrophils from nonasthmatics
with allergic rhinitis. Using a threshold chemotaxis speed of about 1.55 mm/min,
the test accurately diagnosed 22 of 23 patients with asthma and 8 of 11
nonasthmatic controls. Next steps include using the test on broader patient
populations with different inflammatory disorders that may affect neutrophil
Published online May 1, 2014
Patent applications filed;
licensed by Salus Discovery LLC;
available for partnerships to develop improved bioassay solutions
Sackmann, E.K.-H. et al.
Proc. Natl. Acad. Sci. USA; published online April 7, 2014;
Contact: David J. Beebe, University of Wisconsin-Madison,
All contents Copyright © 1993-2015 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]