Thursday, May 9, 2013
Publication and contact
Gene expression signature
as a prostate cancer prognostic
A 32-gene expression
signature could help guide the choice of postoperative treatment for prostate
cancer. Bioinformatic analysis of the expression of 1,536 genes in malignant
prostate tissue isolated from patients with prostate cancer following radical
prostatectomy identified a 32-gene expression signature that correlated with
outcome. The signature was validated in a blinded cohort of 270 patients, in
which it had greater prognostic value than existing clinical markers. Next
steps include looking prospectively to test whether the expression signature
predicts disease progression.
The work was carried out in collaboration with the bioTheranostics Inc.
subsidiary of bioMerieux S.A.
Published online May 9, 2013
Patented; unavailable for
Wu, C.-L. et al. Proc.
Natl. Acad. Sci. USA; published online March 26, 2013;
Contact: W. Scott McDougal, Massachusetts General Hospital,
All contents Copyright © 1993-2016 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]