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Carbamylated serum albumin as a risk factor for mortality in end-stage renal disease (ESRD)

Carbamylated serum albumin could be a useful marker of increased mortality risk in patients with ESRD. In two cohorts totaling
1,348 patients with ESRD, a higher percentage of carbamylated serum albumin was associated with a higher risk of death. Next steps could include determining if reducing the levels of carbamylated serum albumin helps lower mortality in animal models for ESRD.

SciBX 6(11); doi:10.1038/scibx.2013.276
Published online March 21, 2013

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Berg, A.H. et al. Sci. Transl. Med.; published online March 6, 2013;
Contact: Anders H. Berg, Beth Israel Deaconess Medical Center, Boston, Mass.