Thursday, January 24, 2013
This week in techniques
Publication and contact
spectroscopy to detect microcalcified breast cancer lesions
Studies of breast cancer
samples suggest diffuse reflectance spectroscopy could help detect
microcalcified breast cancer lesions during standard biopsies. Breast cancer
biopsy techniques target microcalcified lesions because lesions lacking
microcalcifications can result in false negative hits. In core biopsy samples
from 23 patients, diffuse reflectance spectra were obtained for cancerous
lesions with and without microcalcifications and for benign lesions. A
computational algorithm incorporating the spectra detected microcalcified
lesions with 97% positive predictive power and 88% negative predictive power.
Next steps include devising a miniature optical fiber probe to conduct the
studies with the needle device currently used in breast biopsies and conducting
a large-scale clinical trial.
Published online Jan. 24, 2013
Patent application filed by
Institutes of Technology and co-inventors; will be
available for licensing in the near future
Soares, J.S. et al.
Proc. Natl. Acad. Sci. USA; published online Dec. 24, 2012;
Contact: Maryann Fitzmaurice, Case Western Reserve
All contents Copyright © 1993-2017 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]