Thursday, October 18, 2012
Publication and contact
Paper-based diagnostic for
A paper-based method for
detecting liver enzymes in the blood could be useful for detecting
drug-related hepatotoxicity in the point-of-care setting. The method consists
of a paper-based microfluidic device that detects the liver enzymes aspartate
aminotransferase (AST) and alanine
aminotransferase (ALT) in a single drop of blood. In
serum and whole-blood samples, the device generated colorimetric readouts
that fell into one of three clinically relevant concentration ranges and
showed over 90% accuracy. Next steps include testing the device in a
third-world hospital setting in Vietnam.
Published online Oct. 18, 2012
available for licensing from Diagnostics
Pollack, N.R. et al.
Sci. Transl. Med.; published online Sept. 19, 2012;
Contact: Jason P. Rolland, Diagnostics for All, Cambridge, Mass.
Contact: Nira R. Pollock, Beth Israel Deaconess Medical Center,
All contents Copyright © 1993-2015 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement
. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions
. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
close [ X ]