ADORAble implants

Researchers at the New York University Langone Medical Center have found a way to ward off a leading cause of joint implant failure.¹ The group has shown that adenosine A2A receptor agonists can block the inflammation and bone destruction that stems from debris particles flaking off the implants. The group now needs to translate the findings into a product that companies can test in the clinic.

Bruce Cronstein, a professor in the Departments of Medicine, Pathology, and Biochemistry and Molecular Pharmacology, said joint implant failure is a bigger problem than in previous decades because the average age of implant recipients today is lower...