BioCentury
ARTICLE | Company News

MacroGenics, Takeda announce second DART deal

October 1, 2014 3:26 AM UTC

MacroGenics Inc. (NASDAQ:MGNX) granted Takeda Pharmaceutical Co. Ltd. (Tokyo:4502) an option to license exclusive, worldwide rights to four programs against undisclosed jointly selected targets. The products will be developed using MacroGenics' Dual-Affinity Re-Targeting (DART) technology.

Takeda will fund all R&D activities and reimburse MacroGenics' expenses. The partners declined to disclose specific indications, but Takeda did say the deal includes autoimmune disorders. MacroGenics is eligible for up to $400 million in milestones, plus double-digit royalties for each product. Additionally, MacroGenics has the option to co-promote each product in the U.S. and may elect to fund a portion of Phase III testing of each product in exchange for an undisclosed North American profit share. ...