BioCentury
ARTICLE | Company News

Abbott sues Folkman, EntreMed, et al.

June 1, 2000 7:00 AM UTC

ABT filed suit in the U.S. District Court for the District of Massachusetts alleging that an ABT scientist discovered the anti-angiogenic activity of the Kringle 5 domain of the plasmogen protein and that ABT should have inventorship of U.S. Patent No. 5,854,221, which covers the use of the Kringle 5 peptide to inhibit endothelial cell proliferation (angiogenesis). The patent was assigned to Judah Folkman and colleagues at Children's Medical Center (Boston, Mass.), and is exclusively licensed to ENMD. The suit alleges that the defendants, including Folkman and ENMD, misappropriated and fraudulently patented the Kringle 5 invention and seeks to reassign ownership of the patent to ABT as well as damages. ...