NCI-Match extends pause in enrollment

NIH's National Cancer Institute said it now plans to resume enrollment in the NCI-Match precision medicine trial in April or May, rather than restarting this month as it had expected. According to NCI's ECOG-ACRIN group, the delay will allow the study's leaders to expand laboratory capabilities to accommodate the volume and pace of patient enrollment, add treatment arms and complete a scientific review of data from the first set of patients.

NCI paused enrollment in November to conduct a planned interim review. The study's protocol required NCI to conduct the review once 500 patients had been enrolled. ECOG-ACRIN said the trial opened in August and enrolled over 800 patients by November, surpassing projections. ...