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Celgene points to other culprits
Monday, June 25, 2001
A letter published in The New England Journal of Medicine last
week implied that Celgene Corp.'s Thalomid thalidomide was responsible for the high level
of deep vein thrombosis (DVT) seen in a suspended Phase II trial of the drug in
combination with doxorubicin and dexamethasone to treat multiple myeloma. But according to
the company, the main culprits are both doxorubicin and the disease itself.
Investigators at the Sloan-Kettering Cancer Center in New York reported
that 4 of 15 patients (27%) with
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