Kinase inhibitor pipeline

Selected biologic and small molecule inhibitors of kinases in clinical development for cancer

Company name Product name Target Most advanced indication Status
Abgenix/Immunex ABX-EGF EGFr Cancer II
AstraZeneca AZD6474 VEGFr Solid tumors Preclin
AstraZeneca Iressa (ZD1839) EGFr Non-small cell lung cancer III
Aventis Flavopiridol Cyclin dependent kinase Cancer IIa